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| Cross Reference | |  | |
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Section 1 - Chemical Product and Company Identification |
| MSDS Name: |
Thiamine hydrochloride
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| Catalog Numbers: |
14899-0000, 14899-0100, 14899-1000
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| Synonyms: |
Vitamin B1 hydrochloride
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| Company Identification:
| Acros Organics BVBA
Janssen Pharmaceuticalaan 3a
2440 Geel, Belgium
| | Company Identification: (USA) | Acros Organics
One Reagent Lane
Fair Lawn, NJ 07410
| | For information in the US, call:
| 800-ACROS-01 |
| For information in Europe, call: | +32 14 57 52 11 |
| Emergency Number, Europe: | +32 14 57 52 99 |
| Emergency Number US: | 201-796-7100 |
| CHEMTREC Phone Number, US:
| 800-424-9300 |
| CHEMTREC Phone Number, Europe:
| 703-527-3887 |
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name: |
% |
EINECS# |
| 67-03-8 |
Thiamine hydrochloride |
98.5-101.5 |
200-641-8 |
| Hazard Symbols: |
XI
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| Risk Phrases: |
36/37/38
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
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Irritating to eyes, respiratory system and skin.
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Potential Health Effects |
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Eye: |
Causes eye irritation.
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Skin: |
Contact with skin causes irritation and possible burns, especially
if the skin is wet or moist. May be harmful if absorbed through the
skin.
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Ingestion: |
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. Low hazard for usual industrial handling.
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Inhalation: |
Dust is irritating to the respiratory tract. May be harmful if
inhaled.
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Chronic: |
Prolonged or repeated skin contact may cause dermatitis.
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Section 4 - First Aid Measures |
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Eyes: |
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
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Skin: |
Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists.
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Ingestion: |
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid. Wash mouth out with water.
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Inhalation: |
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
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Notes to Physician: |
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures |
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General Information: |
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Containers may explode when heated. Dangerous fire
hazard in the form of dust when exposed to heat or flame.
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Extinguishing Media: |
Use water spray, dry chemical, carbon dioxide, or chemical foam.
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Section 6 - Accidental Release Measures |
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General Information: |
Use proper personal protective equipment as indicated in Section 8.
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Spills/Leaks: |
Vacuum or sweep up material and place into a suitable disposal
container.
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Section 7 - Handling and Storage |
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Handling: |
Avoid breathing dust, vapor, mist, or gas. Avoid ingestion and
inhalation.
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Storage: |
Store in a cool, dry place. Store in a tightly closed container.
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Section 8 - Exposure Controls, Personal Protection |
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Engineering Controls:
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Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
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Exposure Limits |
| CAS# 67-03-8: |
| Personal Protective Equipment
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Eyes: |
Wear chemical splash goggles.
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Skin: |
Wear appropriate protective gloves to prevent skin
exposure.
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Clothing: |
Wear appropriate protective clothing to prevent skin
exposure.
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Respirators: |
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
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Section 9 - Physical and Chemical Properties |
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Physical State: | Crystalline powder |
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Color: | white - almost white
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Odor: | Not available |
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pH: | 2.7-3.4 (10 g/L) |
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Vapor Pressure: | Not available |
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Viscosity: | Not available |
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Boiling Point: | Not available |
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Freezing/Melting Point: | 246 - 254 deg C(decom) |
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Autoignition Temperature: | Not available |
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Flash Point: | Not available |
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Explosion Limits: Lower: | Not available |
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Explosion Limits: Upper: | Not available |
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Decomposition Temperature: | |
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Solubility in water: | 1 g/ml |
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Specific Gravity/Density: | |
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Molecular Formula: | C12H17ClN4OS.HCl |
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Molecular Weight: | 337.26 |
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Section 10 - Stability and Reactivity |
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Chemical Stability: |
Light sensitive. Hygroscopic: absorbs moisture or water from the
air. May decompose violently on heating.
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Conditions to Avoid: |
Incompatible materials, excess heat, exposure to moist air or water,
direct sunlight..
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Incompatibilities with Other Materials |
Metals, strong oxidizing agents, strong oxidizing agents, reducing
agents, bases, nitro compounds (organic, e.g. nitrobenzene,
nitroglycerine, picric acid, trinitrotoluene), iodine, tannin,
mercury bichloride, sulfides.
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Hazardous Decomposition Products |
Hydrogen chloride, nitrogen oxides, carbon monoxide, oxides of
sulfur, carbon dioxide, nitrogen.
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Hazardous Polymerization |
Will not occur.
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Section 11 - Toxicological Information |
| RTECS#: |
CAS# 67-03-8: XI7350000
| | LD50/LC50: |
RTECS:
CAS# 67-03-8: Oral, mouse: LD50 = 8224 mg/kg;
Oral, rat: LD50 = 3710 mg/kg;
.
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Carcinogenicity: |
Thiamine hydrochloride -
Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
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Other: |
See actual entry in RTECS for complete information. The toxicological
properties have not been fully investigated.
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Section 12 - Ecological Information |
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Ecotoxicity: |
Fish: Rainbow trout: > 100 mg/L; 96H; LC50
Daphnia: Daphnia: > 100
mg/L; 48H; EC50
Algae: > 100 mg/L; 72H; EBC50
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Section 13 - Disposal Considerations |
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Dispose of in a manner consistent with federal, state, and local regulations.
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Section 14 - Transport Information |
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| IATA
| IMO
| RID/ADR
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| Shipping Name:
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Not regulated.
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Not regulated.
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Not regulated.
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| Hazard Class:
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| UN Number:
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| Packing Group:
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Section 15 - Regulatory Information |
| European/International Regulations |
| European Labeling in Accordance with EC Directives |
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Hazard Symbols: XI
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Risk Phrases: |
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R 36/37/38 Irritating to eyes, respiratory system
and skin.
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| Safety Phrases: |
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S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
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S 37/39 Wear suitable gloves and eye/face
protection.
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| WGK (Water Danger/Protection) |
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| Canada |
| CAS# 67-03-8 is listed on Canada's DSL List |
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| US Federal |
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TSCA |
| CAS# 67-03-8 is listed on the TSCA Inventory. |
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Section 16 - Other Information |
| MSDS Creation Date: |
7/16/1996 |
| Revision #1 Date |
12/15/2004 |
| Revisions were made in Sections: |
General revision. |
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