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Thermo Fisher Scientific Inc
  
Material Safety Data Sheet
5-Hydroxy-p-naphthoquinone
Section 1 - Chemical Product and Company Identification
MSDS Name: 5-Hydroxy-p-naphthoquinone
Catalog Numbers: 12164-0000, 12164-0010, 12164-0050
Synonyms: Juglone; 5-Hydroxy-1,4-naphthalenedione
Company Identification: Acros Organics BVBA
Janssen Pharmaceuticalaan 3a
2440 Geel, Belgium
Company Identification: (USA)Acros Organics
One Reagent Lane
Fair Lawn, NJ 07410
For information in the US, call: 800-ACROS-01
For information in Europe, call: +32 14 57 52 11
Emergency Number, Europe: +32 14 57 52 99
Emergency Number US:201-796-7100
CHEMTREC Phone Number, US: 800-424-9300
CHEMTREC Phone Number, Europe: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS# Chemical Name: % EINECS#
481-39-0 5-Hydroxy-p-naphthoquinone 97% 207-567-5
Hazard Symbols: T
  
Risk Phrases: 25 36/37/38
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Toxic if swallowed. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion: May cause irritation of the digestive tract. Poison by ingestion.
Inhalation: Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid immediately. Wash mouth out with water.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Section 7 - Handling and Storage
Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage: Do not store in direct sunlight. Keep refrigerated. (Store below 4°C/39°F.) Store in a tightly closed container. Store in a dry area.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 481-39-0:
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
Physical State: Crystalline powder
Color: brown - orange
Odor: Not available
pH: Not available
Vapor Pressure: Not available
Viscosity: Not available
Boiling Point: Not available
Freezing/Melting Point: 161 - 163 deg C
Autoignition Temperature: Not available
Flash Point: Not available
Explosion Limits: Lower:Not available
Explosion Limits: Upper:Not available
Decomposition Temperature: Not available
Solubility in water: soluble in hot water
Specific Gravity/Density:
Molecular Formula: C10H6O3
Molecular Weight: 174.16
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures. Light sensitive.
Conditions to Avoid: Incompatible materials, light.
Incompatibilities with Other Materials Strong oxidizing agents, strong reducing agents, strong bases.
Hazardous Decomposition Products Carbon monoxide, carbon dioxide.
Hazardous Polymerization Will not occur.
Section 11 - Toxicological Information
RTECS#: CAS# 481-39-0: QJ5775000
LD50/LC50: RTECS:
CAS# 481-39-0: Oral, mouse: LD50 = 2500 ug/kg;
Oral, rat: LD50 = 112 mg/kg;
.
Carcinogenicity: 5-Hydroxy-p-naphthoquinone - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Other: The toxicological properties have not been fully investigated. See actual entry in RTECS for complete information.
Section 12 - Ecological Information
Not available
Section 13 - Disposal Considerations
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - Transport Information
IATA IMO RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* TOXIC SOLID, ORGANIC, N.O.S. TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1 6.1 6.1
UN Number: 2811 2811 2811
Packing Group: III III III
Section 15 - Regulatory Information
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 25 Toxic if swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 28A After contact with skin, wash immediately with plenty of water.
S 37/39 Wear suitable gloves and eye/face protection.
S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
WGK (Water Danger/Protection)
CAS# 481-39-0: Not available
Canada
CAS# 481-39-0 is listed on Canada's DSL List
US Federal
TSCA
CAS# 481-39-0 is not listed on the TSCA Inventory. It is for research and development use only.
Section 16 - Other Information
MSDS Creation Date: 7/16/1996
Revision #2 Date 6/28/2007
Revisions were made in Sections: 1, 7, 10, 14

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantibility or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential, or exemplary damages howsoever arising, even if the company has been advised of the possibility of such damages.
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